Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.61 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GGT1 | P19440 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29432883 | 0.87 | PTGS2 (0.68) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL338196 | 0.87 | PTGS2 (0.68) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| Iodide SCHEMBL30619798 | 0.85 | PTGS2 (0.65) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| Ethylene SCHEMBL28225928 | 0.83 | PTGS2 (0.63) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL29350633 | 0.83 | MAPK1 (0.62) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL10387591 | 0.82 | PTGS2 (0.62) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL8676653 | 0.81 | PTGS2 (0.61) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL10496464 | 0.81 | PTGS2 (0.61) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL236191 | 0.79 | CA12 (0.59) | PTGS2KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL361220 | 0.79 | PTGS2 (0.59) | PTGS2KDM4EALDH1A1BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156194-A1 | COMPOSITIONS AND METHODS FOR INHIBITING INFLUENZA RNA POLYMERASE PA ENDONUCLEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-14 | — | — | WO | disclosed |