Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | HINT1 | P49773 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14594720 | 1.00 | ADORA3 (0.50) | ADORA3HPGDADORA2AHINT1NT5E | |
| SCHEMBL18636462 | 0.90 | ADORA2A (0.51) | ADORA3HPGDADORA2AHINT1NT5E | |
| SCHEMBL31225342 | 0.90 | ADORA2A (0.51) | ADORA3HPGDADORA2AHINT1NT5E | |
| SCHEMBL19352402 | 0.89 | ADORA3 (0.49) | ADORA3HPGDADORA2AHINT1NT5E | |
| SCHEMBL546453 | 0.89 | ADORA3 (0.51) | ADORA3HPGDADORA2AHINT1NT5E | |
| SCHEMBL4844756 | 0.89 | ADORA3 (0.51) | ADORA3HPGDADORA2AHINT1NT5E | |
| SCHEMBL6537055 | 0.89 | ADORA3 (0.53) | ADORA3HPGDADORA2AHINT1NT5E | |
| SCHEMBL19352192 | 0.88 | ADORA2A (0.48) | ADORA3HPGDADORA2ANT5EPDE3A | |
| SCHEMBL19352194 | 0.88 | ADORA2A (0.48) | ADORA3HPGDADORA2ANT5EPDE3A | |
| SCHEMBL545903 | 0.88 | ADORA3 (0.52) | ADORA3HPGDADORA2AHINT1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155923-A1 | NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2017-09-14 | — | — | WO | disclosed |