Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | HINT1 | P49773 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | ADA | P00813 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18636462 | 1.00 | ADORA2A (0.51) | ADORA2AHINT1HPGDADORA3NT5E | |
| SCHEMBL19352193 | 0.90 | ADORA3 (0.50) | ADORA2AHINT1HPGDADORA3NT5E | |
| SCHEMBL14594720 | 0.90 | ADORA3 (0.50) | ADORA2AHINT1HPGDADORA3NT5E | |
| SCHEMBL20250995 | 0.90 | ADORA2A (0.53) | ADORA2AHINT1HPGDADORA3NT5E | |
| SCHEMBL6429463 | 0.89 | HPGD (0.49) | ADORA2AHINT1HPGDADORA3NT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL10819905 | 0.89 | ADORA2A (0.65) | ADORA2AHINT1HPGDADORA3NT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL14842089 | 0.89 | ADORA2A (0.65) | ADORA2AHINT1HPGDADORA3NT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL10208618 | 0.89 | ADORA2A (0.65) | ADORA2AHINT1HPGDADORA3NT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL12758165 | 0.89 | ADORA2A (0.65) | ADORA2AHINT1HPGDADORA3NT5E | |
| 2'-B-Methyl-Guanosine SCHEMBL21007207 | 0.89 | ADORA2A (0.65) | ADORA2AHINT1HPGDADORA3NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024183748-A1 | LOCKED NUCLEOSIDE CAP ANALOGUE AND USE | 江苏申基生物科技有限公司 | 2024-09-12 | — | — | WO | disclosed |