SCHEMBL19353003

SCHEMBL19353003

COc1ccc(-c2ccc(Oc3ccc(C(=O)c4cccc(C(=O)c5ccc(C)cc5)c4)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 2/20 0.52
ALDH1A1 P00352 2/20 0.51
GAA P10253 2/20 0.51
MMP13 P45452 1/20 0.50
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.49
GLA P06280 1/20 0.49
CTSL P07711 1/20 0.49
RXFP1 Q9HBX9 2/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
PARP10 Q53GL7 1/20 0.47
HPGD P15428 1/20 0.47
TUBB4A P04350 1/20 0.47
TUBB P07437 1/20 0.47
TUBA3C P0DPH7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16948014 1.00 STS (0.52) STSALDH1A1GAAMMP13LMNA
SCHEMBL13026416 0.96 STS (0.56) STSALDH1A1GAAMMP13LMNA
SCHEMBL10014130 0.96 STS (0.56) STSALDH1A1GAAMMP13LMNA
SCHEMBL10014132 0.96 STS (0.56) STSALDH1A1GAAMMP13LMNA
SCHEMBL19353008 0.94 HPGD (0.53) STSALDH1A1GAAMMP13LMNA
SCHEMBL13297321 0.91 HTT (0.53) STSALDH1A1GAAMMP13LMNA
SCHEMBL14407936 0.91 LMNA (0.56) ALDH1A1GAAMMP13LMNAKDM4E
SCHEMBL757809 0.91 LMNA (0.56) ALDH1A1GAAMMP13LMNAKDM4E
SCHEMBL12276577 0.91 STS (0.60) STSALDH1A1GAALMNAKDM4E
SCHEMBL22365124 0.91 LMNA (0.56) ALDH1A1GAAMMP13LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3426741-B1 POLYARYLETHER KETONE COMPOSITIONS AND METHOD OF COATING A METAL SURFACE SOLVAY SPECIALTY POLYMERS USA (US) 2020-10-21 EP disclosed
EP-3494163-B1 POLY(ARYL ETHER KETONE) (PAEK) COMPOSITIONS INCLUDING A LOW MOLECULAR WEIGHT AROMATIC COMPOUND SOLVAY SPECIALTY POLYMERS USA (US) 2020-10-07 EP disclosed
WO-2017153290-A1 POLYARYLETHER KETONE COMPOSITIONS AND METHOD OF COATING A METAL SURFACE SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-09-14 WO disclosed