Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19353227 | 1.00 | DPP8 (0.39) | DPP8DPP7EPHX2 | |
| SCHEMBL20881692 | 0.80 | DPP8 (0.37) | DPP8DPP7 | |
| SCHEMBL24994550 | 0.80 | DPP8 (0.37) | DPP8DPP7 | |
| SCHEMBL16846933 | 0.79 | TEAD1 (0.43) | DPP8DPP7 | |
| SCHEMBL11950456 | 0.79 | TEAD1 (0.43) | DPP8DPP7 | |
| SCHEMBL19240545 | 0.79 | TEAD1 (0.43) | DPP8DPP7 | |
| SCHEMBL24093854 | 0.77 | CPN1 (0.41) | DPP8DPP7EPHX2 | |
| SCHEMBL8354764 | 0.76 | F2 (0.41) | DPP8DPP7 | |
| SCHEMBL24127538 | 0.73 | — | — | |
| SCHEMBL20109371 | 0.72 | DPP8 (0.38) | DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156495-A1 | COMPOUNDS AND METHODS FOR MODULATING BRUTON'S TYROSINE KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |