Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23177636 | 0.88 | EPHX2 (0.34) | DPP8DPP7GAA | |
| SCHEMBL20109923 | 0.82 | DPP8 (0.33) | DPP8DPP7 | |
| SCHEMBL20881692 | 0.77 | DPP8 (0.37) | DPP8DPP7 | |
| SCHEMBL24994550 | 0.77 | DPP8 (0.37) | DPP8DPP7 | |
| SCHEMBL16015437 | 0.76 | CHRNB2 (0.46) | DPP8DPP7TACR3 | |
| SCHEMBL25633195 | 0.76 | CHRNB2 (0.46) | DPP8DPP7TACR3 | |
| SCHEMBL21780895 | 0.76 | DPP8 (0.36) | DPP8DPP7 | |
| SCHEMBL18724922 | 0.74 | DPP8 (0.38) | DPP8DPP7TACR3 | |
| SCHEMBL26790983 | 0.74 | HPGD (0.45) | DPP8DPP7 | |
| SCHEMBL24093854 | 0.73 | CPN1 (0.41) | DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534152-B1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-02 | — | — | EP | disclosed |