Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20881692 | 1.00 | DPP8 (0.37) | DPP8DPP7TEAD1TEAD3 | |
| SCHEMBL15472508 | 0.82 | THRA (0.41) | TEAD1TEAD3 | |
| SCHEMBL19999887 | 0.81 | — | — | |
| SCHEMBL16846933 | 0.80 | TEAD1 (0.43) | DPP8DPP7TEAD1TEAD3 | |
| SCHEMBL19240545 | 0.80 | TEAD1 (0.43) | DPP8DPP7TEAD1TEAD3 | |
| SCHEMBL19353227 | 0.80 | DPP8 (0.39) | DPP8DPP7 | |
| SCHEMBL11950456 | 0.80 | TEAD1 (0.43) | DPP8DPP7TEAD1TEAD3 | |
| SCHEMBL19353225 | 0.80 | DPP8 (0.39) | DPP8DPP7 | |
| SCHEMBL20109371 | 0.77 | DPP8 (0.38) | DPP8DPP7 | |
| SCHEMBL20381627 | 0.75 | PHGDH (0.36) | DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018002-B2 | Certain chemical entities, compositions, and methods | NEUPHARMA, INC (US) | 2024-06-25 | — | — | US | disclosed |
| US-20230043970-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043970-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | BRAF, PIK3CA, PLK1 | DPP8 3375/4885DPP7 3052/4885TEAD1 3933/4885 |
| US-12018002-B2 | Certain chemical entities, compositions, and methods | BRAF, PIK3CA, PLK1 | DPP8 3375/4885DPP7 3052/4885TEAD1 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.