Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 14/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354356 | 0.91 | PDE1B (0.36) | PDE2APDE1BTBXAS1MAPTLMNA | |
| SCHEMBL19354351 | 0.83 | PDE1B (0.32) | PDE2APDE1BTBXAS1MAPTLMNA | |
| SCHEMBL19354355 | 0.81 | PDE1B (0.39) | PDE2APDE1BMAPTLMNAKDM4E | |
| SCHEMBL19354353 | 0.77 | PDE1B (0.44) | PDE2APDE1BMAPTLMNAKDM4E | |
| SCHEMBL19354354 | 0.77 | PDE1B (0.42) | PDE2APDE1BMAPTLMNAKDM4E | |
| SCHEMBL19354358 | 0.73 | MEN1 (0.34) | PDE2APDE1BMAPTLMNAKDM4E | |
| SCHEMBL29921576 | 0.72 | PDE1B (0.41) | PDE2APDE1BMAPTLMNAKDM4E | |
| SCHEMBL30678371 | 0.72 | PDE1B (0.42) | PDE1BKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL30523321 | 0.71 | PDE1B (0.38) | PDE2APDE1BMAPTLMNAKDM4E | |
| SCHEMBL30523334 | 0.69 | BMPR1B (0.42) | PDE2APDE1BMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156262-A1 | ACYCLIC ANTIVIRALS | ALIOS BIOPHARMA, INC. (US) | 2017-09-14 | — | — | WO | disclosed |