SCHEMBL19354514

SCHEMBL19354514

CC(C#N)CC(C)C(C)CC(C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 5/20 0.48
TAAR1 Q96RJ0 4/20 0.45
AOC3 Q16853 2/20 0.41
TSHR P16473 1/20 0.41
RIPK1 Q13546 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CACNA1F O60840 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
ADRA2B P18089 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10490930 0.92 TRPA1 (0.52) TRPA1TAAR1AOC3TSHRRIPK1
SCHEMBL3672929 0.76 TRPA1 (0.67) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL13203017 0.76 TRPA1 (0.44) TRPA1TAAR1TSHRMEN1KMT2A
SCHEMBL13159378 0.76 TRPA1 (0.51) TRPA1TAAR1AOC3TSHRRIPK1
SCHEMBL17038679 0.74 TRPA1 (0.59) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL3864354 0.72 TRPA1 (0.61) TRPA1TAAR1AOC3RIPK1CACNA1F
SCHEMBL9579271 0.72 TRPA1 (0.61) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL508412 0.72 TRPA1 (0.61) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL23520955 0.72 TRPA1 (0.37) TRPA1TAAR1TSHRALDH1A1ALOX15
SCHEMBL2760210 0.71 TAAR1 (0.52) TRPA1TAAR1AOC3TSHRRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170260382-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY APPLYING SAME LG CHEM, LTD. (KR) 2017-09-14 US disclosed