Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354585 | 0.83 | GAA (0.36) | AOC3 | |
| SCHEMBL9384051 | 0.78 | DPP4 (0.39) | DPP4F2 | |
| SCHEMBL9090443 | 0.78 | SMN1; SMN2 (0.46) | KDM4EL3MBTL1LMNAALDH1A1AOC3 | |
| Hydrochloric Acid SCHEMBL9985742 | 0.77 | DPP4 (0.38) | DPP4ALDH1A1F2 | |
| SCHEMBL22885976 | 0.76 | CYP1A2 (0.42) | — | |
| SCHEMBL19354588 | 0.74 | TSHR (0.38) | L3MBTL1ALDH1A1 | |
| SCHEMBL11531757 | 0.74 | KMT2A (0.35) | DPP4KDM4EL3MBTL1ALDH1A1F2 | |
| SCHEMBL7510243 | 0.74 | KMT2A (0.44) | DPP4KDM4EL3MBTL1ALDH1A1F2 | |
| SCHEMBL19354497 | 0.73 | CYP1A2 (0.34) | KDM4ELMNAALDH1A1 | |
| SCHEMBL82461 | 0.72 | DPP4 (0.65) | DPP4KDM4EADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765064-B1 | Alpha-hydroxy-beta-azido-tetrazoles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-19 | — | — | US | disclosed |
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CYP8B1, HSD3B1, HSD17B1 | DPP4 2161/4885KDM4E 2351/4885L3MBTL1 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.