Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354544 | 0.93 | L3MBTL1 (0.69) | L3MBTL1NPSR1RAB9ANPC1MAPT | |
| SCHEMBL19321987 | 0.85 | HRH3 (0.46) | L3MBTL1NPSR1HRH3SLC29A1MEN1 | |
| SCHEMBL9937837 | 0.82 | NPSR1 (0.47) | L3MBTL1NPSR1HRH3HTR2AHTR2C | |
| SCHEMBL10084676 | 0.81 | L3MBTL1 (0.77) | L3MBTL1NPSR1RAB9ANPC1MAPT | |
| SCHEMBL17213613 | 0.80 | L3MBTL1 (0.75) | L3MBTL1NPSR1RAB9ANPC1HRH3 | |
| SCHEMBL19317315 | 0.80 | HRH3 (0.42) | L3MBTL1NPSR1MAPTHRH3HTR2A | |
| SCHEMBL10084675 | 0.78 | L3MBTL1 (0.97) | L3MBTL1NPSR1RAB9ANPC1MEN1 | |
| SCHEMBL19321989 | 0.77 | HRH3 (0.50) | L3MBTL1NPSR1HRH3SLC29A1MEN1 | |
| SCHEMBL19354720 | 0.77 | HRH3 (0.39) | L3MBTL1NPSR1HRH3SLC29A1MEN1 | |
| SCHEMBL9044225 | 0.75 | L3MBTL1 (0.61) | L3MBTL1RAB9ANPC1ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |