SCHEMBL17213613

SCHEMBL17213613

Cc1cccc(C(=O)OCCN2CCCCC2)c1

nearest known ligand 0.75

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.75
NPSR1 Q6W5P4 1/20 0.71
NPC1 O15118 1/20 0.64
RAB9A P51151 1/20 0.64
KMT2A Q03164 4/20 0.60
MEN1 O00255 2/20 0.60
HPGD P15428 2/20 0.54
HRH3 Q9Y5N1 1/20 0.53
KDM4E B2RXH2 1/20 0.52
CYP2D6 P10635 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10084676 0.99 L3MBTL1 (0.77) L3MBTL1NPSR1NPC1RAB9AKMT2A
SCHEMBL10084675 0.87 L3MBTL1 (0.97) L3MBTL1NPSR1NPC1RAB9AKMT2A
SCHEMBL19354544 0.85 L3MBTL1 (0.69) L3MBTL1NPSR1NPC1RAB9AKMT2A
SCHEMBL21783765 0.84 NPSR1 (0.67) L3MBTL1NPSR1KMT2AMEN1HPGD
SCHEMBL14066338 0.83 KMT2A (0.76) L3MBTL1NPSR1RAB9AKMT2AMEN1
SCHEMBL501868 0.83 KMT2A (0.75) NPSR1KMT2AMEN1HPGDKDM4E
SCHEMBL19321937 0.82 KMT2A (0.66) L3MBTL1NPSR1KMT2AMEN1HPGD
Hydrochloric Acid SCHEMBL8481680 0.81 KMT2A (0.73) NPSR1KMT2AMEN1HPGDKDM4E
Water SCHEMBL8479966 0.81 KMT2A (0.73) NPSR1KMT2AMEN1HPGDKDM4E
SCHEMBL501862 0.81 KMT2A (0.72) NPSR1KMT2AMEN1HPGDCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2800566-B1 THERAPEUTIC USE OF IMIDAZOPYRIDINE DERIVATIVES SANOFI SA (FR) 2015-10-28 EP disclosed