Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.74 |
| ▸ | MAOB | P27338 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PHGDH | O43175 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.56 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19357243 | 0.90 | MGLL (0.70) | MGLLMAOBKMT2APHGDHNPSR1 | |
| SCHEMBL19357074 | 0.86 | MGLL (1.00) | MGLLMAOBKMT2APHGDHMAPT | |
| SCHEMBL19357083 | 0.85 | PHGDH (0.77) | MGLLPHGDHHPGDLMNA | |
| SCHEMBL16227143 | 0.82 | ALDH1A1 (0.73) | MAOBKMT2ANPSR1MAPTKDM4E | |
| SCHEMBL31350986 | 0.81 | MAOB (1.00) | MGLLMAOBKMT2ANPSR1MAPT | |
| SCHEMBL19380447 | 0.79 | PHGDH (0.72) | KMT2APHGDHHPGDALDH1A1LMNA | |
| SCHEMBL27545187 | 0.79 | KMT2A (0.74) | MGLLMAOBKMT2ANPSR1MAPT | |
| SCHEMBL2153249 | 0.78 | TDP1 (0.67) | MAOBKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL19380443 | 0.78 | PHGDH (0.66) | MGLLKMT2APHGDHMAPTKDM4E | |
| SCHEMBL19380449 | 0.77 | PHGDH (0.70) | KMT2APHGDHHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157882-A1 | SERINE BIOSYNTHETIC PATHWAY INHIBITORS | Université Catholique de Louvain (BE) | 2017-09-21 | — | — | WO | claimed |
| WO-2017157882-A1 | SERINE BIOSYNTHETIC PATHWAY INHIBITORS | Université Catholique de Louvain (BE) | 2017-09-21 | — | — | WO | disclosed |
| WO-2017157882-A1 | SERINE BIOSYNTHETIC PATHWAY INHIBITORS | Université Catholique de Louvain (BE) | 2017-09-21 | — | — | WO | disclosed |