Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963655 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KMT2AATMMAPK1L3MBTL1 | |
| SCHEMBL6889409 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KMT2AATMMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30878143 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KMT2AATMMAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6889405 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KMT2AATMMAPK1L3MBTL1 | |
| SCHEMBL7373116 | 0.82 | CTSK (0.54) | CTSKCTSLCTSBCTSSCAPN1 | |
| SCHEMBL7092274 | 0.82 | ALDH1A1 (0.58) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL1747758 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KMT2AATMMAPK1L3MBTL1 | |
| SCHEMBL8694600 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KMT2AATMMAPK1L3MBTL1 | |
| SCHEMBL1549936 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPK1L3MBTL1SLC6A2 | |
| Hydrochloric Acid SCHEMBL8649093 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AATMMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017158151-A1 | PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-09-21 | — | — | WO | disclosed |