Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sucrosofate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 5/20 | 0.65 |
| ▸ | FGF2 | P09038 | 5/20 | 0.65 |
| ▸ | SERPINC1 | P01008 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 13/20 | 0.32 |
| ▸ | VEGFA | P15692 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sucrosofate SCHEMBL16661862 | 0.93 | FGF1 (0.74) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL145070 | 0.93 | FGF1 (0.74) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL18467935 | 0.93 | FGF1 (0.74) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL145069 | 0.93 | FGF1 (0.74) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL16661861 | 0.93 | FGF1 (0.74) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL18742107 | 0.92 | FGF1 (0.72) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL921799 | 0.92 | FGF1 (0.72) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL2063889 | 0.90 | FGF1 (0.65) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Sucrosofate SCHEMBL18244210 | 0.90 | FGF1 (0.65) | FGF1FGF2SERPINC1HPSEVEGFA | |
| Water SCHEMBL41379 | 0.83 | FGF1 (0.61) | FGF1FGF2SERPINC1HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051799-A1 | VINORELBINE TARTRATE LIPOSOME, AND RAW MATERIAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海济煜医药科技有限公司 | 2023-04-06 | — | — | WO | disclosed |
| CN-109310782-A | Ephrin receptor A2(EphA2) targeted docetaxel generating nanoliposome composition | 梅里麦克制药股份有限公司 | 2019-02-05 | — | — | CN | disclosed |
| EP-3429631-A1 | TREATING EPHRIN RECEPTOR A2 (EPHA2) POSITIVE CANCER WITH TARGETED DOCETAXEL-GENERATING NANO-LIPOSOME COMPOSITIONS | Merrimack Pharmaceuticals, Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| EP-3429629-A1 | EPHRIN RECEPTOR A2 (EPHA2)-TARGETED DOCETAXEL-GENERATING NANO-LIPOSOME COMPOSITIONS | Merrimack Pharmaceuticals, Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| WO-2017161071-A1 | TREATING EPHRIN RECEPTOR A2 (EPHA2) POSITIVE CANCER WITH TARGETED DOCETAXEL-GENERATING NANO-LIPOSOME COMPOSITIONS | MERRIMACK PHARMACEUTICALS, INC (US) | 2017-09-21 | — | — | WO | disclosed |
| WO-2017161067-A1 | EPHRIN RECEPTOR A2 (EPHA2)-TARGETED DOCETAXEL-GENERATING NANO-LIPOSOME COMPOSITIONS | MERRIMACK PHARMACEUTICALS, INC (US) | 2017-09-21 | — | — | WO | disclosed |