Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360637 | 0.85 | RORC (0.51) | RORCLMNA | |
| SCHEMBL19360361 | 0.82 | RORC (0.61) | RORC | |
| SCHEMBL19360519 | 0.80 | RORC (0.49) | RORCLMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL19360525 | 0.78 | RORC (0.68) | RORC | |
| SCHEMBL19360485 | 0.78 | RORC (0.51) | RORCOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL19360551 | 0.78 | RORC (0.56) | RORC | |
| SCHEMBL19360646 | 0.78 | RORC (0.51) | RORC | |
| SCHEMBL22512504 | 0.77 | RORC (0.51) | RORC | |
| SCHEMBL19360359 | 0.75 | RORC (0.62) | RORC | |
| SCHEMBL19360336 | 0.75 | RORC (0.55) | RORCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |