Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360637 | 0.85 | RORC (0.51) | RORCSMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL19360335 | 0.81 | RORC (0.69) | RORC | |
| SCHEMBL19360559 | 0.78 | RORC (0.73) | RORC | |
| SCHEMBL19360430 | 0.78 | RORC (0.59) | RORCNR1H4MAPT | |
| SCHEMBL19360638 | 0.78 | RORC (0.63) | RORCSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19360452 | 0.78 | RORC (0.63) | RORCSMN1; SMN2NR1H4MEN1KMT2A | |
| SCHEMBL19360531 | 0.77 | RORC (0.58) | RORCNR1H4MAPT | |
| SCHEMBL19360331 | 0.76 | RORC (0.74) | RORCNR1H4 | |
| SCHEMBL19360643 | 0.76 | RORC (0.61) | RORC | |
| SCHEMBL19360598 | 0.75 | EPHX2 (0.48) | RORCSMN1; SMN2NR1H4ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |