Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.59 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | STAMBP | O95630 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360531 | 0.90 | RORC (0.58) | RORCLSSEPHX2PPARGPPARA | |
| SCHEMBL19360643 | 0.87 | RORC (0.61) | RORCEPHX2PPARG | |
| SCHEMBL19360444 | 0.85 | RORC (0.79) | RORC | |
| SCHEMBL19360584 | 0.81 | RORC (0.48) | RORCLSSEPHX2PPARGPPARA | |
| SCHEMBL19360556 | 0.81 | RORC (0.51) | RORCEPHX2PPARGNR1H4MAPT | |
| SCHEMBL22512495 | 0.80 | RORC (0.53) | RORCPSMD14STAMBP | |
| SCHEMBL19360448 | 0.79 | RORC (0.65) | RORCPPARA | |
| SCHEMBL19360598 | 0.79 | EPHX2 (0.48) | RORCEPHX2PPARGPPARANR1H4 | |
| SCHEMBL19360654 | 0.78 | RORC (0.50) | RORCLSSEPHX2PPARGPPARA | |
| SCHEMBL19360336 | 0.78 | RORC (0.55) | RORCNR1H4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |