Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.51 |
| ▸ | RORC | P51449 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.41 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360521 | 0.88 | RORC (0.48) | KIF11RORCACSS2EPHX2ECE1 | |
| SCHEMBL19360580 | 0.84 | RORC (0.63) | KIF11RORCNOTUMCYP2C9 | |
| SCHEMBL30076050 | 0.82 | RORC (0.52) | KIF11RORCNOTUMCYP2C9TAOK1 | |
| SCHEMBL19360425 | 0.82 | RORC (0.52) | KIF11RORCNOTUMCYP2C9TAOK1 | |
| SCHEMBL19360593 | 0.82 | KDM4E (0.43) | KIF11RORCKDM4EACSS2NOTUM | |
| SCHEMBL19360388 | 0.82 | RORC (0.55) | RORCKDM4EACSS2APOBEC3AAPOBEC3G | |
| SCHEMBL30076091 | 0.79 | RORC (0.53) | KIF11RORCNOTUMEPHX2 | |
| SCHEMBL20635386 | 0.79 | RORC (0.53) | KIF11RORCNOTUMEPHX2 | |
| SCHEMBL19360605 | 0.79 | IDH1 (0.47) | RORCKDM4EACSS2APOBEC3AAPOBEC3G | |
| SCHEMBL20822497 | 0.78 | RORC (0.53) | KIF11RORCNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |