Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 6/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360594 | 0.89 | RORC (0.42) | KDM4ERORCACSS2KMT2APTGER4 | |
| SCHEMBL19360388 | 0.85 | RORC (0.55) | KDM4ERORCACSS2IDH1 | |
| SCHEMBL19360322 | 0.85 | RORC (0.49) | RORCKIF11IDH1TLR2TLR1 | |
| SCHEMBL19360539 | 0.83 | RORC (0.46) | KDM4ERORCIDH1TLR2TLR1 | |
| SCHEMBL19360520 | 0.82 | KIF11 (0.51) | KDM4ERORCACSS2KIF11NOTUM | |
| SCHEMBL19360556 | 0.79 | RORC (0.51) | RORCPTGER4PPARG | |
| SCHEMBL19360339 | 0.79 | RORC (0.64) | RORC | |
| SCHEMBL18440914 | 0.78 | RORC (0.52) | KDM4ERORCRAB9AKMT2AIDH1 | |
| SCHEMBL19360616 | 0.77 | KDM4E (0.48) | KDM4ERORCACSS2RAB9AIDH1 | |
| SCHEMBL19360605 | 0.76 | IDH1 (0.47) | KDM4ERORCACSS2IDH1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107531679-A | Aromatic amides analog derivative, its preparation method and its application in medicine | 江苏恒瑞医药股份有限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |