Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360548 | 0.89 | RORC (0.49) | RORCMRGPRX4PPARG | |
| SCHEMBL19360326 | 0.89 | RORC (0.49) | RORCEPHX2NR1H4PPARGPPARA | |
| SCHEMBL19360379 | 0.84 | RORC (0.65) | RORC | |
| SCHEMBL19360574 | 0.84 | RORC (0.65) | RORCMRGPRX4PPARG | |
| SCHEMBL19360317 | 0.81 | RORC (0.65) | RORCMRGPRX4 | |
| SCHEMBL19360368 | 0.81 | RORC (0.63) | RORCEPHX2PPARG | |
| SCHEMBL19360306 | 0.80 | RORC (0.65) | RORCMRGPRX4EPHX2PPARG | |
| SCHEMBL19360387 | 0.80 | RORC (0.81) | RORC | |
| SCHEMBL19360322 | 0.78 | RORC (0.49) | RORC | |
| SCHEMBL19360371 | 0.76 | RORC (0.62) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |