Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.49 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360548 | 0.89 | RORC (0.49) | RORCKIF11IDH1TLR2TLR1 | |
| SCHEMBL19360326 | 0.89 | RORC (0.49) | RORC | |
| SCHEMBL19360378 | 0.86 | RORC (0.64) | RORCIDH1 | |
| SCHEMBL19360593 | 0.85 | KDM4E (0.43) | RORCKIF11IDH1TLR2TLR1 | |
| SCHEMBL19360303 | 0.84 | RORC (0.64) | RORCKIF11 | |
| SCHEMBL19360580 | 0.83 | RORC (0.63) | RORCKIF11 | |
| SCHEMBL19360539 | 0.83 | RORC (0.46) | RORCIDH1TLR2TLR1 | |
| SCHEMBL19360575 | 0.82 | RORC (0.65) | RORCKIF11 | |
| SCHEMBL19360320 | 0.79 | RORC (0.82) | RORC | |
| SCHEMBL19360367 | 0.78 | RORC (0.66) | RORCKIF11IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531679-B | Aromatic amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-07-02 | — | — | CN | disclosed |
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |