Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 13/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360508 | 0.88 | RORC (0.64) | RORC | |
| SCHEMBL19360400 | 0.81 | RORC (0.51) | RORC | |
| SCHEMBL19360653 | 0.78 | RORC (0.62) | RORC | |
| SCHEMBL19360638 | 0.78 | RORC (0.63) | RORCPOLB | |
| SCHEMBL19360452 | 0.78 | RORC (0.63) | RORCPOLB | |
| SCHEMBL19360519 | 0.76 | RORC (0.49) | RORCMAPTPOLBTP53 | |
| SCHEMBL28579311 | 0.75 | RORC (0.61) | RORC | |
| SCHEMBL19360649 | 0.74 | RORC (0.43) | RORCMAPTTP53 | |
| SCHEMBL19360310 | 0.74 | RORC (0.77) | RORC | |
| SCHEMBL19360514 | 0.73 | RORC (0.62) | RORCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |