Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360651 | 0.92 | KMT2A (0.43) | RORCKMT2AMAPT | |
| SCHEMBL19360641 | 0.91 | ALDH1A1 (0.48) | KMT2ATP53LMNAMAPTMLLT1 | |
| SCHEMBL19360519 | 0.87 | RORC (0.49) | RORCTP53LMNAMAPTMLLT1 | |
| SCHEMBL19360568 | 0.85 | RORC (0.61) | RORC | |
| SCHEMBL19360531 | 0.79 | RORC (0.58) | RORCMAPT | |
| SCHEMBL22512561 | 0.78 | RORC (0.52) | RORC | |
| SCHEMBL19360566 | 0.78 | RORC (0.58) | RORC | |
| SCHEMBL19360598 | 0.77 | EPHX2 (0.48) | RORC | |
| SCHEMBL19360569 | 0.77 | RORC (0.57) | RORC | |
| SCHEMBL19360650 | 0.77 | KMT2A (0.42) | RORCKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017157332-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATIONS THEREOF | 江苏恒瑞医药股份有限公司 | 2017-09-21 | — | — | WO | disclosed |