Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.72 |
| ▸ | BTK | Q06187 | 3/20 | 0.67 |
| ▸ | ITK | Q08881 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9923762 | 0.94 | EGFR (0.82) | EGFRBTKITK | |
| SCHEMBL19360698 | 0.91 | EGFR (0.87) | EGFRBTK | |
| SCHEMBL19360699 | 0.91 | EGFR (0.87) | EGFRITK | |
| SCHEMBL9923763 | 0.91 | EGFR (0.82) | EGFRBTKITK | |
| SCHEMBL19360697 | 0.87 | EGFR (0.74) | EGFRBTKITK | |
| SCHEMBL9923759 | 0.87 | EGFR (0.81) | EGFRBTKITK | |
| SCHEMBL9923758 | 0.86 | EGFR (0.82) | EGFRBTKITK | |
| SCHEMBL19360705 | 0.86 | EGFR (0.74) | EGFRBTKITK | |
| SCHEMBL2718173 | 0.84 | EGFR (1.00) | EGFRBTK | |
| SCHEMBL2716652 | 0.84 | EGFR (1.00) | EGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765038-B2 | Heteroaryl compounds and uses thereof | CELGENE CAR LLC (BM) | 2017-09-19 | — | — | US | disclosed |