SCHEMBL19361237

SCHEMBL19361237

CNCc1ccccc1Oc1ccc(I)cc1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 18/20 0.71
HTR2A P28223 12/20 0.71
KCNH2 Q12809 11/20 0.61
SLC6A2 P23975 7/20 0.54
SLC6A3 Q01959 6/20 0.54
CYP2D6 P10635 1/20 0.46
MCL1 Q07820 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3134684 0.86 SLC6A4 (0.75) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL20852556 0.85 SLC6A4 (0.73) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL19361290 0.85 SLC6A4 (0.73) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL6947509 0.83 SLC6A4 (0.71) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL6152176 0.81 SLC6A4 (0.68) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL22910542 0.80 SLC6A4 (0.67) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL6152090 0.80 SLC6A4 (0.66) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL6151984 0.80 SLC6A4 (0.66) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL18401370 0.77 SLC6A4 (0.75) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
SCHEMBL3842045 0.75 ALDH1A1 (0.58) SLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200397927-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2020-12-24 US disclosed
US-20170266326-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2017-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170266326-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 SLC6A4 229/4885HTR2A 562/4885KCNH2 2249/4885
US-20200397927-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS FABP3, TNNI3, TNNT2 SLC6A4 229/4885HTR2A 562/4885KCNH2 2249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.