Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 12/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.32 |
| ▸ | EPX | P11678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433098 | 0.84 | MPO (0.56) | MPOOPRM1OPRD1OPRK1EPX | |
| SCHEMBL19363911 | 0.77 | MPO (0.78) | MPOEPX | |
| SCHEMBL19358571 | 0.73 | MPO (0.70) | MPOEPX | |
| SCHEMBL19358547 | 0.73 | MPO (0.79) | MPOEPX | |
| SCHEMBL19363796 | 0.71 | MPO (0.54) | MPOOPRM1OPRD1OPRK1EPX | |
| SCHEMBL19363798 | 0.70 | MPO (0.64) | MPOOPRM1OPRD1OPRK1EPX | |
| SCHEMBL19358579 | 0.68 | MPO (0.80) | MPOEPX | |
| SCHEMBL19358459 | 0.68 | MPO (0.80) | MPOEPX | |
| SCHEMBL22433068 | 0.68 | MPO (0.56) | MPO | |
| SCHEMBL19358433 | 0.68 | MPO (0.68) | MPOEPX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017160632-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-21 | — | — | WO | disclosed |