Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484286 | 0.85 | — | — | |
| SCHEMBL10717497 | 0.71 | CA12 (0.55) | ALDH1A1CYP2C9ALOX15CYP2C19HSD17B10 | |
| SCHEMBL5182502 | 0.71 | CA12 (0.55) | ALDH1A1CYP2C9ALOX15CYP2C19HSD17B10 | |
| SCHEMBL505727 | 0.71 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1965547 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL10718760 | 0.70 | CA12 (0.52) | ALDH1A1CYP2C9ALOX15CYP2C19HSD17B10 | |
| SCHEMBL3360351 | 0.69 | CA12 (0.62) | ALDH1A1CYP2C9HPGDALOX15CYP2C19 | |
| SCHEMBL817631 | 0.69 | — | — | |
| SCHEMBL11444273 | 0.68 | ACE2 (0.38) | ALOX15 | |
| Carbamic Acid SCHEMBL28243838 | 0.68 | GABRR1 (0.43) | ALDH1A1GABRR1GGT1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331558-A2 | PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS | Agilent Technologies, Inc. (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010034024-A2 | PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS | AGILENT TECHNOLOGIES, INC. (US) | 2010-03-25 | — | — | WO | disclosed |