SCHEMBL505727

SCHEMBL505727

CC(N)NCCNC(C)N

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
LMNA P02545 2/20 0.30
CNR1 P21554 1/20 0.30
ADRA1A P35348 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661203 0.86 ALDH1A1 (0.32) ALDH1A1
SCHEMBL9592948 0.86 ALDH1A1 (0.32) ALDH1A1
SCHEMBL180016 0.83
SCHEMBL9720442 0.83 GRIA1 (0.35) ALDH1A1
SCHEMBL1484286 0.83
SCHEMBL23838528 0.83
SCHEMBL8457986 0.83 GRIA1 (0.35) ALDH1A1
SCHEMBL6722313 0.83 GRIA1 (0.35) ALDH1A1
SCHEMBL8736110 0.83 LMNA (0.33) TSHRLMNACNR1ADRA1ATDP1
SCHEMBL20762441 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12215177-B2 Contaminant remediation with functionalized (meth)acrylic polymer or copolymer macroparticulates and systems related thereto COUNTERTRACE LLC (US) 2025-02-04 US claimed
US-20240117093-A1 CONTAMINANT REMEDIATION WITH FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND SYSTEMS RELATED THERETO COUNTERTRACE LLC (US) 2024-04-11 US claimed
US-20220259350-A1 CONTAMINANT REMEDIATION WITH FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND SYSTEMS RELATED THERETO COUNTERTRACE LLC (US) 2022-08-18 US claimed
US-20220259351-A1 FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND METHODS FOR PRODUCTION AND USE THEREOF COUNTERTRACE LLC (US) 2022-08-18 US claimed
EP-3997189-A1 CONTAMINANT REMEDIATION WITH FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND SYSTEMS RELATED THERETO Countertrace LLC (US) 2022-05-18 EP claimed
EP-3997136-A1 FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND METHODS FOR PRODUCTION AND USE THEREOF Countertrace LLC (US) 2022-05-18 EP claimed
WO-2021007441-A1 CONTAMINANT REMEDIATION WITH FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND SYSTEMS RELATED THERETO COUNTERTRACE LLC (US) 2021-01-14 WO claimed
WO-2021007432-A1 FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND METHODS FOR PRODUCTION AND USE THEREOF COUNTERTRACE LLC (US) 2021-01-14 WO claimed
US-20250115695-A1 CONTAMINANT REMEDIATION WITH FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND SYSTEMS RELATED THERETO COUNTERTRACE LLC (US) 2025-04-10 US disclosed
US-12215177-B2 Contaminant remediation with functionalized (meth)acrylic polymer or copolymer macroparticulates and systems related thereto COUNTERTRACE LLC (US) 2025-02-04 US disclosed
US-12076340-B2 Use of trientine to deliver copper to ischemic tissue INNOLIFE CO., LTD. (CN) 2024-09-03 US disclosed
US-20240117093-A1 CONTAMINANT REMEDIATION WITH FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND SYSTEMS RELATED THERETO COUNTERTRACE LLC (US) 2024-04-11 US disclosed
US-11795150-B2 Synthesis of triethylenetetramines PHILERA NEW ZEALAND LIMITED (NZ) 2023-10-24 US disclosed
US-20220259351-A1 FUNCTIONALIZED (METH)ACRYLIC POLYMER OR COPOLYMER MACROPARTICULATES AND METHODS FOR PRODUCTION AND USE THEREOF COUNTERTRACE LLC (US) 2022-08-18 US disclosed
US-20060041170-A1 starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride PHILERA NEW ZEALAND LIMITED (NZ) 2006-02-23 US disclosed
US-20030232799-A1 Copper chelators for treating ocular Inflammation LI, NING, DR. (CN) 2003-12-18 US disclosed
EP-1370254-A2 COPPER CHELATORS FOR TREATING OCULAR INFLAMMATION The University of British Columbia (CA) 2003-12-17 EP disclosed
US-20030055113-A1 Copper chelators for treating ocular inflammation UNIVERSITY OF BRITISH COLUMBIA, THE (CA) 2003-03-20 US disclosed
WO-2002043722-A2 COPPER CHELATORS FOR TREATING OCULAR INFLAMMATION THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-06-06 WO disclosed
US-5863879-A POLYMER IS FORMED BY REACTING A POLYMER CONTAINING VINYLAMINE UNIT WITH COMPOUNDS CONTAINING ALDEHYDE OR KETO GROUPS AND OPTIONAL OTHER AMINE OR ALOCHOL CONTAINING COMPOUNDS SUCH AS AMINAL, HEMIAMINAL OR AMINAL ACETATE BASF AKTIENGESELLSCHAFT (DE) 1999-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795150-B2 Synthesis of triethylenetetramines PNMT, TES, TPR ALDH1A1 4075/4885TSHR 932/4885MAPK1 3313/4885
US-12076340-B2 Use of trientine to deliver copper to ischemic tissue HIF1A, HIF1AN, P4HA1 ALDH1A1 40/4885TSHR 1099/4885MAPK1 3257/4885
US-20060041170-A1 starting the reaction of alkylating ethylenediamine with formaldehyde to form pure triethylenetetramine; salt formation of triethylenetetramine disuccinate or triethylenetetramine tetrahydrochloride TET1, TET2, TET3 ALDH1A1 3779/4885TSHR 982/4885MAPK1 3022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.