Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364011 | 0.96 | P2RX3 (0.73) | P2RX3P2RX2 | |
| SCHEMBL30215907 | 0.91 | P2RX3 (0.67) | P2RX3P2RX2 | |
| SCHEMBL2249103 | 0.91 | P2RX3 (0.67) | P2RX3P2RX2 | |
| SCHEMBL19363991 | 0.91 | P2RX3 (0.85) | P2RX3P2RX2 | |
| SCHEMBL18084465 | 0.90 | P2RX3 (0.68) | P2RX3P2RX2 | |
| SCHEMBL5529795 | 0.89 | P2RX3 (0.65) | P2RX3P2RX2 | |
| Hydrochloric Acid SCHEMBL30215848 | 0.88 | P2RX3 (0.64) | P2RX3P2RX2 | |
| Hydrochloric Acid SCHEMBL21315695 | 0.88 | P2RX3 (0.64) | P2RX3P2RX2 | |
| SCHEMBL5525622 | 0.84 | P2RX3 (0.70) | P2RX3P2RX2 | |
| SCHEMBL1494018 | 0.84 | P2RX3 (0.70) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430000-B1 | PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR | AFFERENT PHARMACEUTICALS INC (US) | 2022-12-28 | — | — | EP | disclosed |
| US-10822311-B2 | Pyrimidines and variants thereof, and uses therefor | Afferent Pharmaceuticals, Inc. (US) | 2020-11-03 | — | — | US | disclosed |
| WO-2017160569-A1 | PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR | AFFERENT PHARMACEUTICALS INC. (US) | 2017-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10822311-B2 | Pyrimidines and variants thereof, and uses therefor | P2RX3, P2RX5, P2RX4 | P2RX3 1/4885P2RX2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.