Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364093 | 0.90 | MPO (0.55) | MPO | |
| SCHEMBL22433068 | 0.78 | MPO (0.56) | MPO | |
| SCHEMBL19363796 | 0.77 | MPO (0.54) | MPO | |
| SCHEMBL19364094 | 0.77 | MPO (0.56) | MPO | |
| SCHEMBL19358448 | 0.76 | MPO (0.57) | MPO | |
| SCHEMBL19363913 | 0.69 | MPO (0.78) | MPO | |
| SCHEMBL19363868 | 0.67 | KDM4A (0.35) | — | |
| SCHEMBL19363870 | 0.64 | SLC6A2 (0.39) | — | |
| SCHEMBL22433098 | 0.64 | MPO (0.56) | MPO | |
| SCHEMBL19363910 | 0.62 | MPO (0.74) | MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017160632-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-21 | — | — | WO | disclosed |