Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364057 | 0.90 | MPO (0.54) | MPO | |
| SCHEMBL19364095 | 0.88 | MPO (0.55) | MPO | |
| SCHEMBL19364094 | 0.87 | MPO (0.56) | MPO | |
| SCHEMBL22433068 | 0.77 | MPO (0.56) | MPO | |
| SCHEMBL19363796 | 0.76 | MPO (0.54) | MPO | |
| SCHEMBL19358434 | 0.76 | MPO (0.57) | MPO | |
| SCHEMBL19363914 | 0.72 | MPO (0.79) | MPO | |
| SCHEMBL19364096 | 0.71 | MPO (0.77) | MPO | |
| SCHEMBL19363913 | 0.70 | MPO (0.78) | MPO | |
| SCHEMBL22433039 | 0.67 | KDM4A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017160632-A1 | TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-21 | — | — | WO | disclosed |