Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 7/20 | 0.94 |
| ▸ | GPBAR1 | Q8TDU6 | 12/20 | 0.79 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.79 |
| ▸ | SLC10A2 | Q12908 | 3/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.79 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.79 |
| ▸ | VDR | P11473 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360964 | 1.00 | SLC10A1 (0.94) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL25943490 | 1.00 | SLC10A1 (0.94) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL19364456 | 1.00 | SLC10A1 (0.94) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL19360997 | 1.00 | SLC10A1 (0.94) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL19360972 | 0.97 | SLC10A1 (0.97) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL17641315 | 0.97 | SLC10A1 (1.00) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL19364451 | 0.97 | SLC10A1 (0.97) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL19360963 | 0.97 | SLC10A1 (1.00) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL19364433 | 0.97 | SLC10A1 (1.00) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 | |
| SCHEMBL19361003 | 0.97 | SLC10A1 (0.97) | SLC10A1GPBAR1NR1H4SLC10A2ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170266206-A1 | POLYMERIC BILE ACID DERIVATIVES INHIBIT HEPATITIS B AND D VIRUS AND NTCP TRANSPORT | HUAHUI HEALTH LTD. (CN) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266206-A1 | POLYMERIC BILE ACID DERIVATIVES INHIBIT HEPATITIS B AND D VIRUS AND NTCP TRANSPORT | SLC10A1, SLC10A2, ABCB11 | SLC10A1 1/4885GPBAR1 17/4885NR1H4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.