Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19364684 | 1.00 | MAPT (0.31) | MAPTHRH3LMNAL3MBTL1 | |
| SCHEMBL8912048 | 0.88 | MAPT (0.32) | MAPTHRH3LMNAL3MBTL1 | |
| SCHEMBL8907693 | 0.88 | MAPT (0.32) | MAPTHRH3LMNAL3MBTL1 | |
| SCHEMBL19578438 | 0.85 | MAPT (0.31) | MAPTHRH3LMNAL3MBTL1 | |
| SCHEMBL18782589 | 0.85 | MAPT (0.31) | MAPTHRH3LMNAL3MBTL1 | |
| SCHEMBL19578134 | 0.83 | CA2 (0.34) | MAPTLMNAL3MBTL1 | |
| SCHEMBL754074 | 0.81 | LMNA (0.38) | MAPTLMNAL3MBTL1 | |
| SCHEMBL890117 | 0.81 | GAA (0.35) | MAPTHRH3LMNAL3MBTL1 | |
| SCHEMBL890065 | 0.81 | GAA (0.35) | MAPTHRH3LMNAL3MBTL1 | |
| SCHEMBL8917506 | 0.80 | CYP1A2 (0.33) | MAPTHRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765087-B2 | Benzimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2017-09-19 | — | — | US | disclosed |