Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.53 |
| ▸ | UBE2M | P61081 | 10/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365784 | 0.85 | POLB (0.47) | UBE2MDCUN1D1 | |
| SCHEMBL19364862 | 0.84 | MAP4K4 (0.45) | CNR2TRPV4 | |
| SCHEMBL19365722 | 0.82 | POLB (0.41) | UBE2MDCUN1D1 | |
| SCHEMBL19670560 | 0.81 | POLB (0.47) | RHOA | |
| SCHEMBL19365571 | 0.81 | MCHR1 (0.42) | — | |
| SCHEMBL19706120 | 0.81 | POLB (0.45) | UBE2MDCUN1D1 | |
| SCHEMBL19365306 | 0.81 | POLB (0.44) | UBE2MDCUN1D1 | |
| SCHEMBL19706137 | 0.80 | MCHR1 (0.43) | UBE2MDCUN1D1 | |
| SCHEMBL19365866 | 0.79 | POLB (0.38) | UBE2MDCUN1D1 | |
| SCHEMBL19365636 | 0.79 | POLB (0.46) | UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |