Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22428317 | 0.81 | ALDH1A1 (0.36) | MAPK1HTTTSHRALDH1A1MEN1 | |
| SCHEMBL19365959 | 0.78 | MAPK1 (0.52) | MAPK1HTTHSD17B10USP2ALOX15 | |
| SCHEMBL5387363 | 0.76 | MAT2A (0.48) | MAPK1HTTHSD17B10USP2ALOX15 | |
| SCHEMBL5376009 | 0.75 | PI4KA (0.51) | MAPK1HTTHSD17B10USP2ALOX15 | |
| SCHEMBL5366008 | 0.72 | MAPK1 (0.46) | MAPK1HTTHSD17B10USP2ALOX15 | |
| SCHEMBL5387360 | 0.69 | MAPK1 (0.46) | MAPK1HTTHSD17B10USP2ALOX15 | |
| SCHEMBL5369247 | 0.69 | MAPT (0.46) | MAPK1HTTHSD17B10TSHRCNR2 | |
| SCHEMBL5376005 | 0.68 | ALDH1A1 (0.49) | MAPK1HTTHSD17B10USP2ALOX15 | |
| SCHEMBL5374675 | 0.68 | MAPT (0.48) | MAPK1HTTHSD17B10TSHRCNR2 | |
| SCHEMBL28952883 | 0.68 | AVPR1A (0.44) | MAPK1HTTHSD17B10ALOX15APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| WO-2017157735-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | WO | disclosed |