Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 13/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19367004 | 0.83 | MAPT (0.32) | — | |
| SCHEMBL20034598 | 0.81 | MRGPRX1 (0.39) | RIPK2FLT1KDR | |
| SCHEMBL19367202 | 0.80 | RIPK2 (0.36) | RIPK2EGFR | |
| SCHEMBL19366938 | 0.79 | CSF1R (0.32) | FLT1KDRCSF1REGFRFGFR1 | |
| SCHEMBL19366602 | 0.76 | MAP2K1 (0.34) | RIPK2FLT1KDR | |
| SCHEMBL19366613 | 0.76 | FLT1 (0.35) | RIPK2FLT1KDRCSF1R | |
| SCHEMBL19366595 | 0.74 | CSF1R (0.44) | FLT1KDRCSF1R | |
| SCHEMBL19366614 | 0.72 | MEN1 (0.54) | FLT1KDRCSF1R | |
| SCHEMBL20034583 | 0.70 | MAP2K1 (0.49) | RIPK2FLT1KDR | |
| SCHEMBL15129534 | 0.69 | MAP2K1 (0.36) | RIPK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804855-B1 | BENZOHETEROCYCLIC COMPOUNDS AND USE THEREOF | SHANGHAI KECHOW PHARMA INC (CN) | 2017-09-20 | — | — | EP | disclosed |