Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 13/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.35 |
| ▸ | SMC2 | O95347 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.35 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19367506 | 0.84 | MAP2K1 (0.33) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL15129478 | 0.82 | BRAF (0.35) | RIPK2MAP2K1SMC2EGFRCSNK2A2 | |
| SCHEMBL19366552 | 0.80 | MAP2K1 (0.35) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL19366554 | 0.80 | RIPK2 (0.40) | RIPK2EGFR | |
| SCHEMBL19367459 | 0.77 | MAP2K1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL19367206 | 0.77 | MAP2K1 (0.38) | RIPK2MAP2K1SMC2EGFRCSNK2A2 | |
| SCHEMBL15129514 | 0.76 | MAP2K1 (0.45) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL15129646 | 0.76 | MAP2K1 (0.49) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL15129492 | 0.74 | MAP2K1 (0.47) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL15129375 | 0.73 | MAP2K1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804855-B1 | BENZOHETEROCYCLIC COMPOUNDS AND USE THEREOF | SHANGHAI KECHOW PHARMA INC (CN) | 2017-09-20 | — | — | EP | disclosed |