Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | CTSC | P53634 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 5/20 | 0.43 |
| ▸ | CDK7 | P50613 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.41 |
| ▸ | CCNK | O75909 | 4/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CCNH | P51946 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937104 | 0.83 | MKNK1 (0.52) | ULK1MKNK1MKNK2CTSCKMT2A | |
| SCHEMBL1937349 | 0.80 | MKNK1 (0.50) | ULK1MKNK1MKNK2CTSCKMT2A | |
| SCHEMBL1935467 | 0.75 | MAPK1 (0.47) | ULK1MKNK1MKNK2CTSCPAK1 | |
| SCHEMBL2103189 | 0.75 | ULK1 (0.65) | ULK1KMT2ABCL6PAK1CDK9 | |
| SCHEMBL27612351 | 0.73 | ULK1 (0.51) | ULK1MKNK1MKNK2KMT2ABCL6 | |
| SCHEMBL11907283 | 0.73 | ULK1 (0.71) | ULK1MKNK1MKNK2CTSCPAK1 | |
| SCHEMBL1936394 | 0.72 | MAPK1 (0.45) | ULK1MKNK1MKNK2CTSCPAK1 | |
| SCHEMBL13057444 | 0.72 | CCNK (0.45) | ULK1MKNK1MKNK2CDK9CDK7 | |
| SCHEMBL11018874 | 0.72 | PAK1 (0.46) | ULK1MKNK1MKNK2CTSCKMT2A | |
| SCHEMBL28933583 | 0.70 | PAK1 (0.47) | ULK1MKNK1MKNK2CTSCKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331524-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025831-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |