Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 8/20 | 0.43 |
| ▸ | CDK9 | P50750 | 7/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1937104 | 0.93 | MKNK1 (0.52) | MAPK1MKNK1MKNK2CDK7CDK9 | |
| SCHEMBL22729058 | 0.88 | MAPK1 (0.66) | MAPK1CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL29220626 | 0.82 | MAPK1 (0.54) | MAPK1MKNK1MKNK2CDK1CCNB1 | |
| SCHEMBL23001261 | 0.82 | CDK2 (0.46) | MAPK1MKNK1MKNK2CDK7CDK9 | |
| SCHEMBL1936394 | 0.81 | MAPK1 (0.45) | MAPK1MKNK1MKNK2CDK7CDK9 | |
| SCHEMBL13057444 | 0.81 | CCNK (0.45) | MAPK1MKNK1MKNK2CDK7CDK9 | |
| SCHEMBL22977477 | 0.81 | CCNE1 (0.68) | CDK9CCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL28933583 | 0.75 | PAK1 (0.47) | MAPK1MKNK1MKNK2CDK7CDK9 | |
| SCHEMBL1937349 | 0.75 | MKNK1 (0.50) | MAPK1MKNK1MKNK2CDK7CDK9 | |
| SCHEMBL1936700 | 0.75 | ULK1 (0.51) | MAPK1MKNK1MKNK2CDK7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331524-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | Bayer CropScience AG (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025831-A1 | HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |
| US-4082535-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |