Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.34 |
| ▸ | SMC2 | O95347 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.34 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19366557 | 0.87 | MAP2K1 (0.33) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL19366949 | 0.84 | MAP2K1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL19366602 | 0.84 | MAP2K1 (0.34) | MAP2K1MAP2K2 | |
| SCHEMBL15129419 | 0.83 | MAP2K1 (0.41) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL19367202 | 0.77 | RIPK2 (0.36) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL15129595 | 0.73 | MAP2K1 (0.56) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL15131429 | 0.71 | MAP2K1 (0.53) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL19366606 | 0.70 | MAP2K1 (0.34) | MAP2K1MAP2K2 | |
| SCHEMBL19347512 | 0.70 | MAP2K1 (0.53) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL15129375 | 0.70 | MAP2K1 (0.34) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2804855-B1 | BENZOHETEROCYCLIC COMPOUNDS AND USE THEREOF | SHANGHAI KECHOW PHARMA INC (CN) | 2017-09-20 | — | — | EP | disclosed |