SCHEMBL1936755

SCHEMBL1936755

O=Cc1cccc(Nc2ncc(C(F)(F)F)c(NC3CC3)n2)c1

nearest known ligand 0.62

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ULK1 O75385 20/20 0.62
ULK2 Q8IYT8 5/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1937038 0.97 ULK1 (0.63) ULK1ULK2
SCHEMBL1937028 0.86 EGFR (0.56)
SCHEMBL1936754 0.85 ULK1 (0.60) ULK1ULK2
SCHEMBL1937628 0.84 ULK1 (0.60) ULK1ULK2
SCHEMBL2509928 0.84 SYK (0.50) ULK1ULK2
SCHEMBL1937742 0.84 CTSC (0.49)
SCHEMBL1937543 0.84 SYK (0.50) ULK1ULK2
SCHEMBL2514310 0.84 SYK (0.46) ULK1ULK2
SCHEMBL17547570 0.84 ULK1 (0.67) ULK1ULK2
SCHEMBL17545176 0.81 ULK1 (0.88) ULK1ULK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110245249-A1 Heterocyclically Substituted Anilinopyrimidines BAYER CROPSCIENCE AG (DE) 2011-10-06 US disclosed
EP-2331533-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES Bayer CropScience AG (DE) 2011-06-15 EP disclosed
WO-2010025850-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245249-A1 Heterocyclically Substituted Anilinopyrimidines POLL, H1-2, H1-0 ULK1 1759/4885ULK2 1288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.