SCHEMBL1936754

SCHEMBL1936754

O=CCc1cccc(Nc2ncc(C(F)(F)F)c(NC3CC3)n2)c1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ULK1 O75385 20/20 0.60
ULK2 Q8IYT8 5/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1937628 0.96 ULK1 (0.60) ULK1ULK2
SCHEMBL1937646 0.86 PRKCQ (0.66)
SCHEMBL1936755 0.85 ULK1 (0.62) ULK1ULK2
SCHEMBL1937720 0.84 CTSC (0.48)
SCHEMBL1937038 0.82 ULK1 (0.63) ULK1ULK2
SCHEMBL17547570 0.82 ULK1 (0.67) ULK1ULK2
SCHEMBL17545176 0.80 ULK1 (0.88) ULK1ULK2
SCHEMBL2511202 0.80 KIT (0.62) ULK1ULK2
SCHEMBL26506688 0.78 ULK1 (0.77) ULK1ULK2
SCHEMBL17545133 0.78 ULK1 (0.74) ULK1ULK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2331533-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES Bayer CropScience AG (DE) 2011-06-15 EP disclosed
WO-2010025850-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-03-11 WO disclosed