Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 7/20 | 0.31 |
| ▸ | DRD4 | P21917 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578492 | 0.75 | SLC6A2 (0.36) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10035307 | 0.75 | SLC6A2 (0.36) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10029425 | 0.75 | ATM (0.34) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18643566 | 0.75 | SLC6A2 (0.36) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL14777110 | 0.74 | SLC6A2 (0.35) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12691975 | 0.73 | MAOB (0.31) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19367689 | 0.72 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL30475183 | 0.72 | ALDH1A1 (0.33) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19367687 | 0.72 | CYP1A2 (0.32) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2230476 | 0.71 | ELANE (0.35) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267707-A1 | Methods and Compositions for Substituted Alpha-Aminophosphonate Analogues | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267707-A1 | Methods and Compositions for Substituted Alpha-Aminophosphonate Analogues | NPEPPS, AGPS, PHOSPHO1 | CYP1A2 4206/4885CYP2A6 2929/4885SLC6A2 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.