Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | EDNRB | P24530 | 2/20 | 0.55 |
| ▸ | EDNRA | P25101 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936151 | 0.90 | PPARG (0.60) | MEN1KMT2ATSHRLMNAHPGD | |
| SCHEMBL12293612 | 0.82 | MEN1 (0.76) | MEN1KMT2ATSHRCYP3A4LMNA | |
| SCHEMBL14243557 | 0.81 | PPARG (0.73) | MEN1KMT2ATSHRCYP3A4LMNA | |
| SCHEMBL12293623 | 0.81 | PPARG (0.58) | LMNAEDNRAALDH1A1PPARGPPARD | |
| SCHEMBL1936834 | 0.79 | PPARG (0.61) | MEN1KMT2ATSHRCYP3A4EDNRB | |
| SCHEMBL533130 | 0.78 | PPARG (0.66) | MEN1KMT2ATSHRCYP3A4LMNA | |
| SCHEMBL12293613 | 0.78 | TCF4 (0.60) | EDNRAPPARGPPARDPPARAPKM | |
| SCHEMBL14702211 | 0.78 | MAPT (0.58) | MEN1KMT2AHPGDEDNRBEDNRA | |
| SCHEMBL12293579 | 0.78 | PPARG (0.57) | LMNAEDNRBEDNRAALDH1A1PPARG | |
| SCHEMBL27030595 | 0.77 | EDNRA (0.61) | MEN1KMT2ALMNAHPGDEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331697-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | University Court of The University of Dundee (GB) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010013071-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-02-04 | — | — | WO | disclosed |