Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | EDNRA | P25101 | 4/20 | 0.55 |
| ▸ | EDNRB | P24530 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TCF4 | P15884 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1936832 | 0.90 | MEN1 (0.57) | PPARGPPARDPPARALMNAHPGD | |
| SCHEMBL12293579 | 0.88 | PPARG (0.57) | PPARGPPARDPPARALMNAMAPT | |
| SCHEMBL12293613 | 0.88 | TCF4 (0.60) | PPARGPPARDPPARAMAPTEDNRA | |
| SCHEMBL14702211 | 0.88 | MAPT (0.58) | PPARGPPARDPPARAHPGDMAPT | |
| SCHEMBL12293572 | 0.86 | CCR2 (0.57) | PPARGPPARDPPARAHPGDMAPT | |
| SCHEMBL12293580 | 0.86 | PPARG (0.56) | PPARGPPARDPPARALMNAMAPT | |
| SCHEMBL12293574 | 0.86 | KDM4E (0.59) | PPARGPPARDPPARALMNAMAPT | |
| SCHEMBL533130 | 0.85 | PPARG (0.66) | PPARGPPARDPPARALMNAMAPT | |
| SCHEMBL14702206 | 0.85 | PKM (0.61) | PPARGPPARDPPARALMNAHPGD | |
| SCHEMBL12293623 | 0.85 | PPARG (0.58) | PPARGPPARDPPARALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263691-A1 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2011-10-27 | — | — | US | claimed |
| EP-2331697-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | University Court of The University of Dundee (GB) | 2011-06-15 | — | — | EP | claimed |
| WO-2010013071-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-02-04 | — | — | WO | claimed |
| US-9155289-B2 | Methods concerning PPAR delta and antagonists thereof | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2015-10-13 | — | — | US | disclosed |
| US-9155289-B2 | Methods concerning PPAR delta and antagonists thereof | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2015-10-13 | — | — | US | disclosed |
| EP-2331697-B1 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIV DUNDEE (GB) | 2015-03-25 | — | — | EP | disclosed |
| US-8895608-B2 | Sulfonamide anti-viral compounds | Kineta, Inc. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8895608-B2 | Sulfonamide anti-viral compounds | Kineta, Inc. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20130039945-A1 | Anti-Viral Compounds | Kineta, Inc. (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130039945-A1 | Anti-Viral Compounds | Kineta, Inc. (US) | 2013-02-14 | — | — | US | disclosed |
| WO-2011133729-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2011-10-27 | — | — | WO | disclosed |
| US-20110263691-A1 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2011-10-27 | — | — | US | disclosed |
| US-20110263691-A1 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2011-10-27 | — | — | US | disclosed |
| EP-2331697-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | University Court of The University of Dundee (GB) | 2011-06-15 | — | — | EP | disclosed |
| EP-2331697-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | University Court of The University of Dundee (GB) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010013071-A3 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-03-25 | — | — | WO | disclosed |
| WO-2010013071-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-02-04 | — | — | WO | disclosed |
| WO-2010013071-A2 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263691-A1 | METHODS CONCERNING PPAR DELTA AND ANTAGONISTS THEREOF | PPARD, PPARG, PPARA | PPARG 2/4885PPARD 1/4885PPARA 3/4885 |
| US-20130039945-A1 | Anti-Viral Compounds | MAVS, EIF2AK2, IRF3 | PPARG 2406/4885PPARD 2888/4885PPARA 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.