Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24484089 | 0.92 | FAAH (0.45) | CASP2TSHRNAAACNR1FAAH | |
| SCHEMBL16273323 | 0.92 | FAAH (0.45) | CASP2TSHRNAAACNR1FAAH | |
| SCHEMBL21153506 | 0.92 | CASP2 (0.44) | CASP2TSHRRECQLNAAAALDH1A1 | |
| SCHEMBL12082159 | 0.90 | CASP2 (0.46) | CASP2TSHRNAAACNR1SMN1; SMN2 | |
| SCHEMBL13598099 | 0.90 | MEN1 (0.41) | CASP2TSHRNAAACNR1FAAH | |
| SCHEMBL20327891 | 0.90 | MEN1 (0.41) | CASP2TSHRNAAACNR1FAAH | |
| SCHEMBL24435855 | 0.89 | FAAH (0.54) | CASP2NAAAFAAHENPP2LPAR1 | |
| SCHEMBL24435860 | 0.89 | FAAH (0.54) | CASP2NAAAFAAHENPP2LPAR1 | |
| SCHEMBL24435906 | 0.89 | FAAH (0.54) | CASP2NAAAFAAHENPP2LPAR1 | |
| SCHEMBL24435928 | 0.89 | FAAH (0.54) | CASP2NAAAFAAHENPP2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017160669-A1 | INSULIN-INCRETIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2017-09-21 | — | — | WO | disclosed |