SCHEMBL193716

SCHEMBL193716

NS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
CA2 P00918 11/20 0.71
CA1 P00915 10/20 0.71
CA9 Q16790 6/20 0.71
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
CA7 P43166 4/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
F2 P00734 2/20 0.56
PRSS1 P07477 2/20 0.56
PRSS2 P07478 2/20 0.56
PRSS3 P35030 2/20 0.56
CA4 P22748 3/20 0.56
CA12 O43570 3/20 0.53
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
PLA2G7 Q13093 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
CA14 Q9ULX7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28228467 0.98 LMNA (0.96) LMNACA2CA1CA9MEN1
Methanesulfonamide SCHEMBL11803937 0.94 LMNA (0.88) LMNACA2CA1CA9MEN1
SCHEMBL3154840 0.93 LMNA (0.88) LMNACA2CA1CA9MEN1
SCHEMBL28384319 0.92 LMNA (0.85) LMNACA2CA1CA9MEN1
SCHEMBL9839080 0.91 LMNA (0.82) LMNACA2CA1CA9MEN1
Formic Acid SCHEMBL27594868 0.90 LMNA (0.81) LMNACA2CA1CA9MEN1
SCHEMBL3149535 0.84 LMNA (0.71) LMNACA2CA1CA9MEN1
SCHEMBL28746782 0.83 LMNA (0.70) LMNACA2CA1CA9MEN1
SCHEMBL10389380 0.83 LMNA (0.69) LMNACA2CA1CA9MEN1
SCHEMBL12283586 0.83 LMNA (0.70) LMNACA2CA1CA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745119-A1 ISOCYANATE COMPOSITION Hanwha Solutions Corporation (KR) 2026-05-20 EP claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
WO-2025128149-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-19 WO claimed
US-20250186630-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING PEPTIDES VIEWPOINT MOLECULAR TARGETING, INC. (US) 2025-06-12 US claimed
CN-119528773-A N-alkylation method of sulfonamide compound 赣南医科大学 2025-02-28 CN claimed
WO-2025042219-A1 ISOCYANATE COMPOSITION 한화솔루션 주식회사 2025-02-27 WO claimed
CN-119233829-A Pharmaceutical composition for preventing, inhibiting or treating symptoms associated with pseudoallergy 学校法人高崎健康福祉大学 2024-12-31 CN claimed
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
CN-118685793-A Synthesis method of thio-N-heterocyclic compound 南阳师范学院 2024-09-24 CN claimed
CN-118176003-A Medicaments comprising P2X4 receptor antagonists for the prevention or treatment of nociceptive pain and/or visceral pain 日本化学药品株式会社 2024-06-11 CN claimed
US-6291514-B1 Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-09-18 US claimed
EP-1069114-A2 Sulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION (US) 2001-01-17 EP claimed
WO-2000047578-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-08-17 WO claimed
EP-0870764-A1 Sulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION (US) 1998-10-14 EP claimed
EP-0757674-A1 SUBSTITUTED SULFONAMIDES AS SELECTIVE $g(b) 3? AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY Merck & Co., Inc. (US) 1997-02-12 EP claimed
EP-0699191-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1996-03-06 EP claimed
WO-1995029159-A1 SUBSTITUTED SULFONAMIDES AS SELECTIVE β3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY MERCK & CO., INC. (US) 1995-11-02 WO claimed
WO-1994027979-A1 SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN IMMUNOPHARMACEUTICS, INC. (US) 1994-12-08 WO claimed
EP-0446748-A2 Use of perylenedyes for the preparation of write, print or copying materials RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1991-09-18 EP claimed
US-4886813-A INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1989-12-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250186630-A1 FIBROBLAST ACTIVATION PROTEIN TARGETING PEPTIDES FAP, FIBP, TPX2 LMNA 1715/4885CA2 1845/4885CA1 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.