Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CCR9 | P51686 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383347 | 0.91 | KIF11 (0.40) | TSHRKIF11ALDH1A1HPGDALOX15 | |
| SCHEMBL19373835 | 0.89 | CYP1A2 (0.35) | TSHRCCR9KIF11ALDH1A1HPGD | |
| SCHEMBL20096916 | 0.84 | KIF11 (0.49) | TSHRCCR9KIF11ALDH1A1HPGD | |
| SCHEMBL19373831 | 0.84 | TSHR (0.45) | TSHRCCR9KIF11ALDH1A1HPGD | |
| SCHEMBL25058962 | 0.82 | TSHR (0.43) | TSHRCCR9KIF11ALDH1A1HPGD | |
| SCHEMBL24617586 | 0.82 | KIF11 (0.47) | KIF11ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL13132809 | 0.81 | TSHR (0.42) | TSHRCCR9KIF11ALDH1A1HPGD | |
| SCHEMBL25648118 | 0.80 | KIF11 (0.39) | KIF11TDP1MAPTKMT2A | |
| SCHEMBL19373829 | 0.79 | NR1I2 (0.43) | TSHRCCR9KIF11ALDH1A1HPGD | |
| SCHEMBL25490702 | 0.77 | KIF11 (0.46) | TSHRCCR9KIF11ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267796-A1 | FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS | DOW GLOBAL TECHNOLOGIES LLC | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267796-A1 | FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS | PARG, AP1M1, BZW1 | TSHR 4307/4885CCR9 1503/4885KIF11 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.