Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25648118 | 0.90 | KIF11 (0.39) | CYP1A2CYP2A6KDM4ELMNAKIF11 | |
| SCHEMBL19373834 | 0.89 | TSHR (0.43) | ALDH1A1HSD17B10KIF11GAAHPGD | |
| SCHEMBL19421847 | 0.86 | DYRK1A (0.42) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL19421844 | 0.82 | TSHR (0.37) | CYP1A2CYP2A6KDM4EALDH1A1LMNA | |
| SCHEMBL15458685 | 0.78 | BCHE (0.42) | KDM4EALDH1A1LMNAHSD17B10KIF11 | |
| SCHEMBL19383347 | 0.76 | KIF11 (0.40) | CYP1A2ALDH1A1LMNAHSD17B10KIF11 | |
| SCHEMBL19421853 | 0.76 | PDGFRA (0.38) | CCR9SMN1; SMN2MAPTACHE | |
| SCHEMBL19373831 | 0.74 | TSHR (0.45) | ALDH1A1HSD17B10KIF11HPGDTSHR | |
| SCHEMBL793554 | 0.73 | GPR3 (0.46) | CYP1A2CYP2A6KDM4EALDH1A1LMNA | |
| SCHEMBL26767517 | 0.73 | HTT (0.36) | CYP1A2KDM4EALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301412-B2 | Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20170267796-A1 | FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS | DOW GLOBAL TECHNOLOGIES LLC | 2017-09-21 | — | — | US | disclosed |
| US-20170267796-A1 | FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS | DOW GLOBAL TECHNOLOGIES LLC | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267796-A1 | FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS | PARG, AP1M1, BZW1 | CYP1A2 680/4885CYP2A6 1096/4885KDM4E 443/4885 |
| US-10301412-B2 | Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers | PARG, AP1M1, BZW1 | CYP1A2 680/4885CYP2A6 1096/4885KDM4E 443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.